Product Description 4-Sachet Plus from Meneesh Pharmaceuticals is an advanced anti-tubercular formulation designed to improve treatment compliance in patients with tuberculosis. It comes in a single-dose sachet form, containing a precise combination of four first-line anti-TB drugs (Rifampicin, Isoniazid, Ethambutol, and Pyrazinamide) along with Pyridoxine (Vitamin B6) to reduce the risk of drug-induced neuropathy. The sachet is granulated using NODS (New Oral Drug System) technology, making it easier to swallow and ensuring uniform drug absorption. With its convenient once-daily sachet format and orange flavour, 4-Sachet Plus improves patient adherence and enhances therapeutic outcomes. Uses Treatment of pulmonary and extrapulmonary tuberculosis Effective in both new and continuation phases of TB treatment (as prescribed) Helps reduce pill burden and simplifies anti-TB therapy Key Benefits Convenient Sachet Form – One sachet covers the full daily dose of multiple TB drugs Improves Compliance – Reduces pill load, making it easier for patients to complete treatment Balanced Combination – Contains all four essential anti-TB drugs in WHO-recommended proportions Enhanced Absorption – NODS granular technology ensures better bioavailability Added Vitamin B6 – Prevents peripheral neuropathy caused by Isoniazid How to Use Take one sachet daily or as directed by your doctor. Mix the sachet contents with water or juice and consume immediately. Follow the full treatment course without skipping doses to avoid drug resistance. How It Works 4-Sachet Plus combines four first-line anti-tubercular drugs: Rifampicin: Kills TB bacteria by inhibiting RNA synthesis. Isoniazid: Stops bacterial cell wall formation. Ethambutol: Prevents bacterial growth by inhibiting cell wall enzymes. Pyrazinamide: Works inside cells to kill dormant TB bacteria. Pyridoxine (Vitamin B6): Protects against nerve damage associated with Isoniazid.Together, they provide a powerful and complete therapy against tuberculosis. Side Effects Nausea, vomiting, or stomach upset Mild skin rash or itching Loss of appetite Fatigue Rare: liver issues, peripheral neuropathy, or vision disturbances(Consult your doctor if any side effects persist or worsen.) Precautions & Warnings Not recommended for patients with severe liver or kidney disease unless prescribed. Avoid alcohol during treatment. Pregnant and breastfeeding women should take only under medical advice. Regular liver function tests may be advised during treatment. Do not stop the treatment early to avoid drug resistance. Storage Instructions Store in a cool, dry place below 25°C. Keep away from direct sunlight and moisture. Keep out of reach of children. FAQs What is 4-Sachet Plus used for? It is used for the treatment of tuberculosis by providing a complete fixed-dose combination of four anti-TB drugs in one sachet. Can I take 4-Sachet Plus without water? No, always mix the sachet contents in water or juice and consume immediately for best results. Does 4-Sachet Plus contain Vitamin B6? Yes, it contains Pyridoxine (Vitamin B6) to prevent Isoniazid-induced neuropathy. How long should I take 4-Sachet Plus? The duration depends on your doctor’s prescription and the TB treatment phase (usually 6–9 months). Can children use 4-Sachet Plus? Use in children should be strictly under a pediatrician’s guidance.